Haloperidol decanoate dosing?

Haloperidol decanoate dosing?

• A. 50-100 mg
• B. 400-600 mg
• C. 150-300 mg
• D. 10-20 mg

Answer: (C)

Haloperidol decanoate is a long-acting injectable given intramuscularly to provide therapeutic coverage for about a month. Because it releases slowly, the dose per injection is much larger than a typical daily oral dose and is chosen to sustain effective levels over 4 weeks. The standard maintenance range is roughly 150 to 300 mg per month, which reflects balancing symptom control with the risk of extrapyramidal symptoms and other adverse effects. Dosing is individualized based on prior oral haloperidol exposure, tolerability, and response, with careful monitoring for EPS, tardive dyskinesia, sedation, and other side effects. Doses outside this range are less likely to maintain balance between efficacy and safety.

Haloperidol decanoate is a long-acting injectable given intramuscularly to provide therapeutic coverage for about a month. Because it releases slowly, the dose per injection is much larger than a typical daily oral dose and is chosen to sustain effective levels over 4 weeks. The standard maintenance range is roughly 150 to 300 mg per month, which reflects balancing symptom control with the risk of extrapyramidal symptoms and other adverse effects. Dosing is individualized based on prior oral haloperidol exposure, tolerability, and response, with careful monitoring for EPS, tardive dyskinesia, sedation, and other side effects. Doses outside this range are less likely to maintain balance between efficacy and safety.